Of Mice And Men Application Essays - English-language Films, Films

Of Mice And Men Application Summary John Steinbeck wrote the book Of Mice & Men in 1937 during the Great Depression. The book is about the lives of two men who travel from job to job working on ranches and farms. These two main characters are George Milton and Lennie Small. George is a short, slight man and Lennie is a large, mildly retarded man. George looks out for Lennie and in return George gets companionship and protection from Lennie. The other characters in the book (all on a ranch near Soledad) are Candy, a "swamper" or handyman, Crooks, a black stable buck, Slim, the jerkline skinner, Curley, the boss's son, and Curley's new young wife. Of Mice & Men starts out with George and Lennie walking from the bus stop to the ranch where they have a new job. On their way to the ranch George instructs Lennie on how to act with their new boss so they don't lose this job, like they lost their previous one. They decide to camp next to a pool of water. They discuss how they are going to spend the money they earn to buy land and start their own farm. They sit by the fire and talk about this dream. George tells Lennie to come back to this camp place if he gets into trouble like he did in the last town. They make their beds next to the fire and go to sleep. The next morning George and Lennie walk the rest of the way to the ranch. They get settled into the bunkhouse and make friends with Candy, who gave them their bed assignments. The boss's son, Curley, comes in looking for his wife and harasses Lennie, even though George tries to answer all Curley's questions. According to Candy, "Curley's like a lot of little guys. He hates big guys. He's alla time picking scraps with big guys. Kind of like he's mad at ?em because he ain't a big guy."(49) George and Lennie also meet Curley's wife. "She had full, rouged lips and wide-spaced eyes, heavily made up. Her fingernails were red."(57) George and Lennie work that afternoon on the ranch and Slim, the jerkline skinner who handles the draft animals at the ranch, is impressed with how strong Lennie is and how much barley he can buck compared to other men. Candy hears George and Lennie talking about the place they are going to get and wants to go in with them. George agrees to let him, because Candy has almost enough money saved up. They all start to believe they can really obtain their dream. Curley enters the bunkhouse looking for his wife. He suspects she is with Slim and when he finds she is not, the men give Curley a bad time about his wife. Curley catches Lennie smiling, and thinks Lennie is laughing at him. He attacks Lennie but Lennie tries to retreat and just stands there and takes it as Curley hits him. Finally George yells "Get him, Lennie," (111) so Lennie grabs Curley's hand and doesn't let go. When Lennie finally lets go of Curley's hand it is crushed. To save Lennie, Slim threatens Curley and he agrees to tell everyone that he caught his hand in a piece of machinery to save face. Slim's dog had puppies and Slim gives Lennie a puppy that Lennie can't leave alone. Lennie is always out in the barn petting his puppy and one time he goes into Crook's room, which is off the barn. Crooks is the old black"stable buck." Crooks tells Lennie no one is allowed in his room, but Lennie doesn't understand and comes in and talks to Crooks anyway. Candy comes into the barn looking for Lennie and finds Lennie with Crooks. Lennie and Candy talk about their plans and Crooks asks if he can work for them. Crooks wants in on the dream too. Later, when Lennie is playing in the barn with his puppy again, the puppy nips at Lennie, so he slaps and kills it by accident. Lennie worries that he will never get to tend the rabbits, as George has been promising. He lays the puppy down and covers him up with hay but then he wants to feel the soft puppy again, so he uncovers it and begins to stroke it. Curley's wife comes in to the barn and startles Lennie. He quickly covers it up again, hoping that she won't notice the dead puppy, but it's too

The House on Mango Stret essays

The House on Mango Stret essays The novel, The House on Mango Street, by Sandra Cisneros is a novel that portrays Latino Women in a society that views them as being second-class citizens. This novel is a great example of diversity. These young women who are growing up in Chicago are dominated by men and are valued for their looks rather than who they really are. Cisneros, through the series of stunning vignettes really wants her readers to envision the obstacles Latino women face in their everyday life. Latino women are not treated The male characters in this novel view women as being objects. This forces the girls to grow up in a society where looks and an appealing appearance are the only important characteristics for women to have. Cisneros describes the main character, Esperanza as being quite different form the other Latino women. Esperanza is not happy with the culture and the society that she lives in. She feels that she will break free from the ties in her lifestyle and that women can be independent. Appearance of Latino women is an extreme importance to them. These women believe that if they are not attractive then the men will not want to marry or date them. Marin is a great example of this belief. She thinks that a great place for a woman to work is downtown, because they get to look their prettiest downtown. Women in Cisneros novel are an example of a diversity that is troubling for women to have. Not only are these women feeling that they need to be beautiful to be accepted as equals, they are living in an area where Latinos alone are not necessarily associated with. Chicago is not an area where an individual would indicate to find an individual who is Latino. This makes it even harder for the women in this novel to live a Not only do women face the struggle with attractiveness, Cisneros indica ...

Describle the signaling pathways responsible for regulating the Research Paper

Describle the signaling pathways responsible for regulating the release of the pancreatic zymogens from the pancreatic acinar ce - Research Paper Example The paper highlights the presence of receptors and secretagogues that initiate the secretion of the zymogens. The main secreatagogues include the acetylcholine, cholecystokinin and other associated peptides. The paper also describes the mechanism of calcium ion signalling pathway in regulating secretion. Moreover, the paper provides details of the secretion mechanism, detailing all the mechanism and their regulation. Regulation of the pancreatic function in the acinar cells is complex, and scientists are yet to describe all the mechanisms in depth. Introduction The functioning of the pancreas presents complex pathways. The organ exhibits both exocrine and endocrine functions. The fact that the peculiar organ exhibits both of these function s has intrigued scientists to unveil the regulatory mechanism that govern its function. As expected, the organ has both neural and hormonal forms of regulation. Pancreatic duct cells secrete a combination of fluid and bicarbonate ions responsible f or the neutralization of gastric contents in the duodenum. Since this secretion involves a duct, it defines the exocrine function of the organ. On the other hand, the pancreas consists of four types of endocrine cells that secrete varying hormones. The alpha cells are responsible for glucagon secretion, while the beta cells produce insulin. In addition, there is production of somatostatin from delta cells, and pancreatic polypeptide from PP cells. Structural studies of the pancreas indicate an assembly of the endocrine cells in the islets. This paper will highlight the regulatory mechanisms of the acinar cells responsible for the secretion of the juices that play a role in digestion. Acinar cells of the pancreas bear the responsibility of synthesis and secretion of the numerous enzymes that aid in digestion of nutrients in the small intestine lumen. The critical function played by the digestive enzymes necessitates the availability of both short and long-term regulation. Such regula tion serves to ensure a supply of the enzymes after food intake. The regulation process requires the availability of receptors and secretagogues that initiate the secretion process (Husain, and Thrower 466-7). Receptors and Secretagogues The primary secretagogues responsible for initiating secretions from acinar cells are acetylcholine and cholecystokinin (CCK) (Wu et al 642). The vagal postganglionic neurons are responsible for the release of acetylcholine. On the other hand, CCK comes from the intestinal endocrine cells. Moreover, secretin, a secretagogue for initiating secretion in duct cells also plays a critical role in the acinar cells. There are numerous receptors for hormones, growth factors, and neurotransmitters in the acinar cells. Studies reveal that activity on these receptors influence the secretion patterns of the acinar cells. CCK has the potential of activating CCK receptors on the vagal afferent endings. Scientists have described the mechanism responsible for this activation as paracrine. Other studies have highlighted that CCK advances to the blood and exerts control on the contractile mechanisms of the gall bladder. This triggers emptying of the bladder. Animal studies have established that CCK receptors play a vital role in the acinar cells of rodents. However, studies are yet to confirm the role of the same in humans. In addition, the acinar cells exhibit effects of other peptides responsible for